THE RELATIONSHIP BETWEEN OF HYPERURICEMIA WITH HYPERGLYCEMIA IN JAVANESE MEN

Abstract

Background: The prevalence of degenerative diseases, especially metabolic diseases in Indonesia in the last 10 years is increasing. Studies of the linkage between hyperuricemia and hyperglycemia have been reported in a clinical context and very limited in a populative context. This study was aimed at analyzing the prevalence of hyperuricemia in Javanese men, by analyzing the relationship between uric acid, Fasting Plasma Glucose, and other anthropometric factors that affect Javanese older males in Central Java, Indonesia.

Methods: The study was conducted by cross-sectional study of men from the general population in Ngebung village (Sragen, Central Java) aged ≥ 50. The sample size of 108 people came from the total population of men aged ≥ 50 of 359 people ( 30%) in the village (Total number of male population in the village is 1133). Measurements include blood uric acid levels, fasting blood glucose, anthropometry (height, weight, waist circumference, and hip). The data were analyzed using Kruskal-Wallis, Spearman, and Binary Logistic Regression statistics.

Results: The results showed that the prevalence of hypouricemia reached 2.8%, normal 46.3%, and hyperuricemia 50.9%. Meanwhile, the prevalence of hypoglycemia was 3.7%, normoglycemia 49.1%, and hyperglycemia 47.2%. The concentration of uric acid had a positive correlation with BMI (r=0.204, p < 0.05), FPG (r=0.184, p ≥ 0.05), and WHR (r=0.107, p > 0.05), but the age variable had a negative correlation (r=-0.016, p > 0.05). After adjusting the age, WHR, and BMI variables, odds ratio showed that hyperuricemia people were 0.29 likely to suffer from hyperglycemia (confidence interval [CI] 95%, 0.12–0.69, p < 0.05).

Conclusions: Therefore, it could be concluded that the older men in that village had a high average of uric acid concentration (50.9% respondents ≥ 7 mg/dL) and hyperuricemia had a positive correlation with hyperglycemia.

Keywords: Relationship, hyperuricemia, hyperglycemia, Javanese

DOI: 10.26553/jikm.2017.8.3.160-168